2008 was a year of many changes for Facebook application developers, culminating with the profile redesign in the fall. Now that several months have passed since the last major round of updates, new apps have begun to ascend the application leaderboards. Which Facebook apps will rise in 2009?

Here’s a look at today’s Top 20 fastest-growing mid-sized applications on Facebook from AppData. These are the top apps in the 100K-1M monthly user range with the highest MAU growth in the last 7 days.

As you can see below, an interesting mix of apps are on the way up. Sponsored apps from Clearasil and Citi sit at #1 and #3 respectively, while Skype’s Video Cards app comes in at #2. There’s the usual smattering of Mob Wars clones, several holiday themed apps, and a couple utilities as well. Which of these do you think are most likely to stick around throughout 2009?

		Name	MAU	Gain	Gain, %	Developer
1.		PixFixApp	164,194	+142,341	+651.4	—
2.		Video Cards with Skype	121,685	+100,073	+463.0	Skype
3.		Citi Magnetic Lyrics	123,998	+48,596	+64.5	—
4.		Send Christmas Spirit	245,182	+77,165	+45.9	Qbiki LLC
5.		MAFFIA NEW	121,253	+37,795	+45.3	—
6.		PageRage Super Profile	373,495	+109,875	+41.7	—
7.		Send and Receive Cards	168,823	+48,704	+40.6	profile.to
8.		Happy Hanukkah!	184,850	+51,162	+38.3	—
9.		Heroes vs. Villains	125,204	+34,012	+37.3	Zynga
10.		zelim ti..	121,834	+29,009	+31.3	—
11.		Send A Christmas Card	149,855	+31,391	+26.5	—
12.		Online Friends	105,132	+19,351	+22.6	Jose Dos Santos
13.		Special Forces	153,642	+26,979	+21.3	—
14.		Thinking of You	678,080	+100,430	+17.4	Patrick Lo
15.		Kiss Me	597,825	+87,195	+17.1	—
16.		Hugs	395,341	+52,099	+15.2	—
17.		Cute Catz	105,381	+13,787	+15.1	Hidden Pixel
18.		Dr. Phil’s Personality Test	498,502	+61,039	+14.0	—
19.		Mob World	230,331	+28,099	+13.9	—
20.		tvClickr	120,231	+14,162	+13.4	LiveHive Systems Inc.